LabCorp 2009 Annual Report Download - page 8

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There are more than 308 million Americans, yet no two are
genetically identical – not even twins. When a person
becomes sick with cancer, an infectious disease or a chronic
health condition, each patient’s unique genetic composition
can help determine how that individual will respond to specifi c
drug therapies, directly affecting prognosis and even survival.
The ability to identify the most effective therapy for an individual
against a debilitating medical condition is a reality today, and
LabCorp is at the forefront of these solutions. Our new test
for the antiplatelet drug Plavix® is an excellent example. The
test identifi es patients who are poor metabolizers of the drug
by discerning a genetic variation in the CYP450 2C19 gene,
helping physicians adjust therapeutic care for the best out-
comes. Similarly, our Trofi le® test is the only clinically validated
test to identify co-receptor tropism in HIV patients. The
Trofi le® test helps guide physicians in their selection of the
best antiviral treatments for individual patient needs. LabCorp
continues to arm physicians with valuable and actionable
diagnostic intelligence, opening the door to a new era of
companion diagnostics and more effective treatment.
Companion
Diagnostics
6 LABORATORY CORPORATION OF AMERICA
PERSONALIZED MEDICINE